2014/10/26

How Much Do You Know About Enzyme

WHAT are enzymes?
Enzymes are macromolecular biological catalysts, which are responsible for thousands of metabolic processes that sustain life. Enzymes are also highly selective catalysts, greatly accelerating both the rate and specificity of metabolic reactions, from the digestion of food to the synthesis of DNA. Most enzymes are proteins, although some catalytic RNA molecules have been identified. It exists in the form of specific three-dimensional structure, and may employ organic and inorganic cofactors to assist in catalysis.

HOW do they work?
Enzymes act by converting starting molecules into different molecules. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates sufficient for life. Enzymes are selective for their substrates and speed up only a few reactions from among many possibilities. The set of enzymes made in a cell determines which metabolic pathways occur in that cell, tissue and organ.

Like all catalysts, enzymes increase the rate of a reaction by lowering its activation energy. Most enzyme reaction rates are millions of times faster than those of comparable un-catalyzed reactions. Just as all catalysts, enzymes will not be consumed by the reactions they catalyze, nor will they alter the equilibrium of these reactions. However, enzymes do differ from most other catalysts for they are highly specific for their substrates.

WHAT function do they have?
Enzymes serve a wide variety of functions inside living organisms.

l  They are indispensable for signal transduction and cell regulation, often via kinases and phosphatases.
l  They also generate movement, with myosin hydrolyzing ATP to generate muscle contraction and also moving cargo around the cell as part of the cytoskeleton.
l  An important function of enzymes is in the digestive systems of animals. Enzymes such as amylases and proteases break down large molecules into smaller ones, so they can be absorbed by the intestines.
l  Enzymes are also involved in more exotic functions, such as luciferase generating light in fireflies. Viruses can also contain enzymes for infecting cells.

About us
Creative Biogene is a US-based manufacturer and provider of genomics and proteomics products and services for academic and governmental research institutes, pharmaceutical and biotechnology industry. The company offers a range of enzymes such as restriction enzyme, polymerases, nucleases, ligases, and reverse transcriptase, nuclease, phosphatase and kinase to perform the most commonly performed nucleic acid modifications. To become the premier provider of innovative technologies, products, unique tools and services for research discoveries and product development in the areas of biological and biomedical research. Emphasis will be placed on the manufacture and distribution of genomics and proteomics based biological research reagent products of the highest possible quality, which include nucleic acid, protein and antibody based research reagent products and services.



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